Chem204: Introduction to Proteomics
Winter Quarter 2010
Starting with a review of protein chemistry, emphasizing chemical modification and separation technologies, the course will review current approaches to the study of proteomics and predict what is likely to be realized in the next several years.
In addition to the lectures, each student will present a review of a published paper selected by the instructors and write a paper on a topic of current interest to the field (from a list provided, or select their own topic after instructor approval).
Provisional Lecture Series
- Overview / Protein Chemistry
- 2D Gels
- Introduction to Mass Spectrometry
- Sample Preparation
- Protein ID 1 – Non-MS
- Protein ID 2 – MS
- Bioinformatics
- PTMs – Overview
- PTMs – Complex / Crosstalk
- Quantitation
- Signaling
- Structural (X-Ray / NMR)
- Biophysical Methods (Fluorescence / Hydrodynamics)
- Protein – Protein Interactions: Non-MS (Y2H; IP)
- Protein – Protein Interactions: TAP Tag; Cross-linking
- Protein Machines / Sociology
- Arrays
- Translational / Biomarkers
- Micro-fluidics / Robotics / HT
- Interaction with other OMICS
For more details contact course organizer: Robert Chalkley.